2020

Targeting VEGF164 in Müller cells may be useful to treat retinopathy of prematurity

In Nature’s Scientific Reports, Becker et al use the Phoenix MICRON IV, OCT, and focal ERG to assess the therapeutic value of knocking down a splice variant of VEGF in Müller cells in a model of Retinopathy of Prematurity (ROP). ROP is characterized by delayed vascularization of the retina after disrupted oxygen levels, followed by

2020

Imaging unanesthetized mice with the Phoenix MICRON™ OCT provides consistent retinal degeneration measurements

In the recently published review, “Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss,” researchers from The Jackson Laboratory in Bar Harbor, Maine and Mahidol University in Bangkok, Thailand performed an extensive literature search to find mouse models of single-gene mutations leading to photoreceptor loss and retinal degeneration. Using the Phoenix MICRON III and

2019

Treating retinitis pigmentosa with cassia seed: Retinal layer analysis with the Phoenix MICRON OCT and Insight software

Retinitis pigmentosa is a genetic disorder that leads to severe vision impairment and blindness. The photoreceptors die off in a self-propelling cycle of rod and cone dysfunction, leading to glial activation and death, leading to more dysfunction. There are a few experimental treatments but no widespread effective treatment or cure. Cassia seed is used in

2019

Phoenix MICRON™ OCT tracks individual stem cells in the rat retina

In the July edition of Nanomedicine journal, Chemla et al demonstrate a fascinating and novel way to label and track individual photoreceptor precursor cells migrating within the retina with fluorescence and gold nanoparticle tagging using the Phoenix MICRON and OCT. Many retinal diseases such as age-related macular degeneration and retinitis pigmentosa are characterized by photoreceptor

2019

The Secret to a Perfect Fundus Image

Hint: It Starts with the Animal Angle   During our hands-on training, we review animal positioning until every user is completely comfortable.  But like most other lab equipment task, it does take some practice.  Aligning the animal just right can be the difference between a great and a good fundus image.  We’ve put together a

2019

ARVO 2019: Frogs, Glue and CNV

Another ARVO passed by in a blur of research, scientific discussions, and seeing science friends. If you came by our booth, thank you for swinging by to chat with the Phoenix team. If you didn’t get a chance, please let me know if you have any questions about the Micron system and look for our

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